Zhangjiagang Clent Chemical Co., Ltd. are mainly engaged in the research, development, manufacturing and trade of pharmaceutical, dye, pesticide and material intermediate products. Our main products are Solvent Yellow 114, cas#75216-45-4 and 2,2-Bipyridine, cas#366-18-7 and Tetrahydropyran-4-one, cas#29943-42-8 and 2,3-Dihydropyran, cas#110-87-2 and 2,3-dihydrofuran,cas#1191-99-7 and 2-Aminothiazole,cas#96-50-4 and other related chemical products.
Flavonoids do not exhibit sufficient activity to be used for chemotherapy, however they can be chemically modified by complexation with metals such as copper (Cu) (II) for instance, in order to be applied for adjuvant therapy. This study investigated the effects of Cu(II) and 2,2′-bipyridine complexation with naringenin on MDA-MB-231 cells. We demonstrated that naringenin complexed with Cu(II) and 2,2′-bipyridine (NGENCuB) was more efficient inhibiting colony formation, proliferation and migration of MDA-MB-231 tumor cells, than naringenin (NGEN) itself.View Detail
2,2′-Bipyridine (bipy or bpy, pronounced ) is an organic compound with the formula C10H8N2. This colorless solid is an important isomer of the bipyridine family. It is a bidentate chelating ligand, forming complexes with many transition metals. Ruthenium complex and platinum complexes of bipy exhibit intense luminescence, which may have practical applications.View Detail
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